| 2026 | Brock Purdy (6) | Mike Evans 39, George Kittle 36, Christian McCaffrey 35 | 1,460 | 14 |
| 2025 | Brock Purdy (9), Mac Jones (8) | Christian McCaffrey 129, Jauan Jennings 90, George Kittle 69 | 4,318 | 33 |
| 2024 | Brock Purdy (15), Joshua Dobbs (1), Brandon Allen (1) | Jauan Jennings 113, George Kittle 94, Deebo Samuel Sr. 81 | 4,424 | 23 |
| 2023 | Brock Purdy (16), Sam Darnold (1) | Brandon Aiyuk 105, George Kittle 90, Deebo Samuel Sr. 89 | 4,577 | 33 |
| 2022 | Jimmy Garoppolo (10), Brock Purdy (5), Trey Lance (2) | Brandon Aiyuk 114, Christian McCaffrey 108, Deebo Samuel Sr. 94 | 4,049 | 30 |
| 2021 | Jimmy Garoppolo (15), Trey Lance (2) | Deebo Samuel Sr. 121, George Kittle 94, Brandon Aiyuk 84 | 4,437 | 26 |
| 2020 | Nick Mullens (8), Jimmy Garoppolo (6), C.J. Beathard (2) | Brandon Aiyuk 96, Kendrick Bourne 74, George Kittle 63 | 4,320 | 25 |
| 2019 | Jimmy Garoppolo (16) | George Kittle 107, Emmanuel Sanders 97, Deebo Samuel Sr. 81 | 4,029 | 28 |
| 2018 | Nick Mullens (8), C.J. Beathard (5), Jimmy Garoppolo (3) | George Kittle 136, Kendrick Bourne 67, Pierre Garcon 46 | 4,247 | 26 |
| 2017 | Brian Hoyer (6), C.J. Beathard (5), Jimmy Garoppolo (5) | Marquise Goodwin 105, Carlos Hyde 88, Pierre Garcon 67 | 4,235 | 15 |
| 2016 | Colin Kaepernick (11), Blaine Gabbert (5) | Jeremy Kerley 115, Quinton Patton 63, Garrett Celek 50 | 3,166 | 21 |
